45 Results for "

Herniaria glabra Linnaeus.

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "Herniaria glabra Linnaeus." in MCE Product Catalog:

12
Glabridin
Glabridin
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12 Publications Verification
Cat. No.: HY-N0393
CAS No.: 59870-68-7
Category:  

Plants Infection Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology Isoflavones

Target:  

PPAR Reactive Oxygen Species (ROS) Bacterial

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities .
9
Engeletin
Engeletin
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9 Cited Publications
Cat. No.: HY-N0436
CAS No.: 572-31-6
Category:  

Plants Flavanonols Liliaceae Flavonoids Microorganisms Phenols Polyphenols Smilacis Glabrae Rhizoma Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
1
Neoliquiritin
Neoliquiritin
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1 Cited Publications
Cat. No.: HY-N2123
CAS No.: 5088-75-5
Category:  

Flavonoids Monophenols Leguminosae Flavonones Phenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Caspase

Neoliquiritin is a flavonoid and flavanone-derived cytotoxic agent with anticancer activity and neuroprotective effects. Neoliquiritin exhibits excellent tumor specificity, exerting a more pronounced killing effect on cancer cells compared with normal oral cells. Neoliquiritin also exerts neuroprotective effects by inhibiting ATP depletion and the elevation of caspase 3/7 activity. Widely present in the roots of Glycyrrhiza uralensis, Glycyrrhiza inflata and Glycyrrhiza glabra, Neoliquiritin can be applied to studies on human oral squamous cell carcinoma, leukemia, Parkinson's disease and other conditions .
1
Glabrone
Glabrone
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1 Cited Publications
Cat. No.: HY-N4194
CAS No.: 60008-02-8
Category:  

Flavonoids Leguminosae Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

PPAR Influenza Virus

Glabrone is an isoflavone found in Glycyrrhiza glabra roots. Glabrone exhibits significant PPAR-γ ligand binding activity. Glabrone is a specific UGT1A9 probe substrate, and its metabolites can block influenza virus release by inhibiting neuraminidase (NA). Glabrone can be used to screen for herb-drug interactions and for anti-influenza virus activity .
Medicagenic acid
Medicagenic acid
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Cat. No.: HY-N2472
CAS No.: 599-07-5
Synonyms: Castanogenin
Category:  

Infection Triterpenes Herniaria glabra Linnaeus. Terpenoids Plants Disease Research Fields Caryophyllaceae

Target:  

Bacterial Xanthine Oxidase

Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
Magnesium isoglycyrrhizinate hydrate
Magnesium isoglycyrrhizinate hydrate
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Cat. No.: HY-154795
CAS No.: 658701-67-8
Purity:  99.81%
Target:  

Caspase NOD-like Receptor (NLR)

Research Areas:  

Inflammation/Immunology

Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant (Glycyrrhiza glabra). Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats .
Licraside
Licraside
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Cat. No.: HY-N6987
CAS No.: 29913-71-1
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

FXR Factor Xa

Licraside, found in Glycyrrhiza glabra, is a Farnesoid X receptor (FXR) activator. Licraside activates FXR to induce upregulation of SHP and BSEP, regulates bile acid homeostasis, reduces elevated biliary and serum TBA, serum ALT, AST, GGT, ALP, and TBIL levels, and attenuates liver histopathological damage. Licraside inhibits factor Xa with an IC50 of 48.54 mM. Licraside can be used for the research of cholestasis and thromboembolic diseases .
Chloranthalactone B
Chloranthalactone B
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Cat. No.: HY-N10913
CAS No.: 66395-03-7
Category:  

Terpenoids Sesquiterpenes Sarcandra glabra (Thunb.) Nakai Chloranthaceae Plants

Target:  

AP-1 p38 MAPK NO Synthase TNF Receptor COX Interleukin Related

Chloranthalactone B, a lindenane-type sesquiterpenoid, is a nature product that could be isolated from Chinese medicinal herb Sarcandra glabra. Chloranthalactone B inhibits the production of inflammatory mediators by inhibiting the AP-1 and p38 MAPK pathways .
3-O-Caffeoylshikimic acid
3-O-Caffeoylshikimic acid
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Cat. No.: HY-W728151
CAS No.: 180981-12-8
Category:  

Livistona chinensis (Jacq.) R. Br. ex Mart. Phenols Polyphenols Plants Palmae

Target:  

Drug Derivative

3-O-Caffeoylshikimic acid is a caffeoylshikimic acid substance and phenolic acid that widely exists in the aerial parts of Equisetum arvense L. and Smilax glabra. During sulfur fumigation processing, 3-O-Caffeoylshikimic acid undergoes chemical transformation to produce 3-O-caffeoylshikimic acid sulfate and 3-O-caffeoylshikimic acid sulfite. At a high concentration (40 μM), 3-O-Caffeoylshikimic acid exhibits cytotoxic activity against human keratinocytes .
Icariside D2
Icariside D2
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Cat. No.: HY-N7450
CAS No.: 38954-02-8
Category:  

Infection Natural Products Plants Annonaceae Disease Research Fields Inflammation/Immunology Annona glabra Linn.

Target:  

Angiotensin-converting Enzyme (ACE) Apoptosis HIV

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis .
Shinpterocarpin
Shinpterocarpin
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Cat. No.: HY-N10144
CAS No.: 157414-04-5
Target:  

PI3K Akt Keap1-Nrf2 Bcl-2 Family SOD Reactive Oxygen Species (ROS)

Research Areas:  

Inflammation/Immunology

Shinpterocarpin is a flavonoid compound. Shinpterocarpin can be isolated from the air-dried roots of Glycyrrhiza glabra L. and Xuanshen Decoction. Shinpterocarpin binds to the targets PI3K, AKT, Nrf2, Bcl-2, Bax, CAT and SOD. Shinpterocarpin enhances immunity and exerts antioxidant effects by reducing the production of ROS .
Glycyrrhizin-6'-methylester
Glycyrrhizin-6'-methylester
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Cat. No.: HY-N11111
CAS No.: 1185255-36-0
Category:  

Triterpenes Leguminosae Terpenoids Plants Glycyrrhiza uralensis Fisch.

Target:  

Others

Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .
Licoflavanone
Licoflavanone
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Cat. No.: HY-N10133
CAS No.: 119240-82-3
Synonyms: 3′-Prenylnaringenin
Category:  

Glycyrrhiza glabra Linn. Flavonoids Leguminosae Flavonones Plants

Target:  

Bacterial mTOR Akt PI3K NF-κB Caspase JNK ERK COX NO Synthase Apoptosis

Licoflavanone (3′-Prenylnaringenin) is a flavanone with antioxidant, anti-inflammatory and anticancer activities. Licoflavanone can be isolated from the leaf extract of Glycyrrhiza glabra. Licoflavanone downregulates the mTOR/PI3K/AKT signaling pathway to inhibit the proliferation, migration and invasion of cancer cells, while activates Bax, Bad and multiple caspase enzymes to induce apoptosis. Its anti-inflammatory effect is manifested by reducing the nuclear translocation of NF-κB, decreasing the phosphorylation levels of p38, JNK and ERK1/2, thereby inhibiting the expression of nitric oxide, proinflammatory cytokines, COX-2 and iNOS. Licoflavanone is used in studies on nasopharyngeal carcinoma and related mechanisms .
Medicagenic acid (Standard)
Medicagenic acid (Standard)
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Cat. No.: HY-N2472R
CAS No.: 599-07-5
Synonyms: Castanogenin (Standard)
Category:  

Triterpenes Herniaria glabra Linnaeus. Terpenoids Plants Caryophyllaceae

Target:  

Xanthine Oxidase Reference Standards Bacterial

Medicagenic acid (Standard) is the analytical standard of Medicagenic acid. This product is intended for research and analytical applications. Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
5-O-(3'-O-Glucosylcaffeoyl)quinic acid
5-O-(3'-O-Glucosylcaffeoyl)quinic acid
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Cat. No.: HY-N8133
CAS No.: 1629852-63-6
Category:  

other families Monophenols Simple Phenylpropanols Other Diseases Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

Others

5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound found in the leaves of Ilex glabra L. Gray (Aquifoliaceae) .
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one
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Cat. No.: HY-N8134
CAS No.: 1809980-25-3
Category:  

Natural Products other families Metabolic Disease Plants Disease Research Fields

Target:  

Dipeptidyl Peptidase

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .
Glychionide A
Glychionide A
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Cat. No.: HY-N8034
CAS No.: 119152-50-0
Category:  

other families Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Apoptosis Autophagy

Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer .
Flavoyadorinin A
Flavoyadorinin A
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Cat. No.: HY-N12713
CAS No.: 20486-38-8
Category:  

Flavonols Flavonoids Plants Orixa japonica Thunb. Salicaceae

Target:  

Others

Flavoyadorinin A is a type of flavonoid compound, and can be found in the Leaves of Viscum album Linnaeus var. coloratum Ohwi Epiphyting to Pyrus communis Linnaeus .
Insecticidal agent 17
Insecticidal agent 17
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Cat. No.: HY-168840
Target:  

Insecticide

Research Areas:  

Others

Insecticidal agent 17 (compound 31) is an insecticidal agent against Plutella xylostella Linnaeus with an LC50 value of 0.759 mg/mL .
Glabrocoumarone A
Glabrocoumarone A
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Cat. No.: HY-125597
CAS No.: 178330-48-8
Synonyms: Kanzonol U
Category:  

Glycyrrhiza glabra Linn. Leguminosae Phenols Polyphenols Plants

Target:  

Others

Glabrocoumarone A (Kanzonol U) is a coumarin identified from G. glabra .
Assay Types